Affinium Launches the Development of a New Class of Antibiotics for Superbugs

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in Drug Treatment

Link: Affinium

Affinium Pharmaceuticals announced today that it has selected a drug candidate for development of a novel MRSA antibiotic to be used in hospital and community settings. The candidate is one of multiple compounds from Affinium’s Galapagos program.

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"It is important that our development candidate operates via a novel mechanism of action with very novel chemistry, and distinct from any other antibiotic on the market. Our drug candidates selectively inhibit a bacterial pathway to kill bacteria without any detectable side effects to the analogous human pathway. Because of their unique way of working, we believe resistance will be slow to develop." said Judd Berman, Ph.D., Senior Vice President of Chemistry. "Our team selected Affinium’s first development candidate after evaluating animal data from over 150 front runner compounds with potent MRSA activity from this new antibiotic class. We selected the first compound for its potential as an IV and oral antibiotic for hospital and community MRSA."

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