Link: European Respiratory Journal.
The adequacy of the initial antibiotic therapy had a marked influence on the rate of CRP decrease, as well as on mortality.
In conclusion, daily C-reactive protein measurements after antibiotic prescription were useful in the identification, as early as day 4, of ventilator-associated pneumonia patients with poor outcome. The identification of the pattern of C-reactive protein response to antibiotics was useful in the recognition of individual clinical course, improving or worsening, as well as of the rate of improvement.
