From the category archives:

MRSA & Opticians

20.23% of the 346 isolates were methicillin-resistant. 33 patients’ isolates (47.15%) fulfilled the definition criteria for CA-MRSA according to the review of the medical charts. The majority of MRSA strains analyzed were isolated from surgical and paediatric patients. The commonest types of infection identified with MRSA were surgical site infections (>70%) whereas for CA-MRSA were conjunctivitis and otitis in 19 patients (57.6%) and accidental skin and subcutaneous tissue infection in 14 patients (42.4 %). The MSSA strains (ST1, ST5, ST15, ST7, ST8, ST25, ST30, ST72, ST80, ST121 and ST508) were heterogeneous by pheno- and genotypic analysis. The first report and genetic analyses of PVL-positive ST88 strain (agr III, SCCmec IV) in Nigeria is shown in this study. ST88 was resistant to trimethoprim-sulfamethoxazole besides to penicillin and oxacillin. CA-MRSA infections are rapidly increasing among young patients with ophthalmologic and auricular infections. Urban regions of lower socioeconomic status and evidence of overcrowding appear to be at higher risk for the emergence of this clone.

via Emergence of a community-associated methicillin-resistant Staphylococcus aureus with unique resistance profile in Southwest of Nigeria — Ghebremedhin et al., 10.1128/JCM.00648-09 — Journal of Clinical Microbiology.

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Topical Eye Antibiotic Besivance Favoured for MRSA

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in MRSA & Opticians

This novel and potent fluoroquinolone designed exclusively for ophthalmic use will gain significant market share of the ocular antibiotics prescribed in the US at the expense of Vigamox (Alcon) and Zymar (Allergan), the current leaders. This will happen because cataract surgeons and contact lens specialists are concerned about the rising incidence of antibiotic resistance and MRSA (methicillin-resistant staph. aureus) infections. When it comes to eye infections (endophthalmitis, bacterial corneal ulcers), there is no margin for error and clinicians will always prescribe the most potent ophthalmic antibiotic available regardless of its cost and insurance formulary coverage.

via Bausch & Lomb’s FDA Approved Topical Eye Antibiotic Besivance (Besif – GLG News.

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