Decoy Makes Sitting Duck Of Superbugs

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in Drug Development

Link: Decoy Makes Sitting Duck Of Superbugs.

A DNA-based therapy could slash the development time of new drugs to combat antibiotic resistant superbugs.

Scientists from the John Innes Centre have proven that by taking a short stretch of DNA from a bacterium and delivering it with an existing antibiotic they can switch off antibiotic resistance.

Together with technology transfer company PBL, the scientists have launched a spin-out company, Procarta Biosystems Ltd, to develop the technology.

"The DNA sequence acts as a decoy, disrupting gene expression and blocking resistance", said Dr Michael McArthur from JIC.

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